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R S McElhinney Selected Research

O(6)-(4-bromothenyl)guanine

11/2005O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts.
1/2000O(6)-(4-bromothenyl)guanine improves the therapeutic index of temozolomide against A375M melanoma xenografts.

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R S McElhinney Research Topics

Disease

1Carcinosarcoma
11/2005
1Neoplasms (Cancer)
08/2003
1Melanoma (Melanoma, Malignant)
01/2000
1Weight Loss (Weight Reduction)
01/2000

Drug/Important Bio-Agent (IBA)

2Temozolomide (Temodar)FDA LinkGeneric
11/2005 - 01/2000
2O(6)-(4-bromothenyl)guanineIBA
11/2005 - 01/2000
1lomeguatribIBA
11/2005
1GuanineIBA
11/2005
1Alkyl and Aryl TransferasesIBA
08/2003
1Alkylating AgentsIBA
08/2003
1O(6)-benzylguanineIBA
01/2000

Therapy/Procedure

1Drug Therapy (Chemotherapy)
08/2003
1Therapeutics
08/2003